The impact of noni juice and grapefruit seed extract (Citrosept) on anaerobic intestinal microbiota
Aleksandra Duda-Chodak , Tomasz Tarko , Paweł Satora , Iwona Drożdż
AbstractThe main aim of the study was to evaluate the impact of Morinda citrifolia L. (noni) juice and grapefruit seed extract (Citrosept) on the growth of representatives of human intestinal microbiota. Pharmaceuticals were added to liquid medium at a final concentration of 1.0, 2.5 or 5.0% and their impact on the bacteria number was assessed by measurement of the turbidity after 24 h of culture. Citrosept had the strongest impact. It inhibited the growth of Bacteroides galacturonicus even at lowest concentration of 1%. The number of Ruminococcus gauvreauii cells was reduced by ~20% only in cultures with 5% Citrosept. Noni juice had diversified impact. In case of Bacteroides galacturonicus, the addition of 5% noni juice to medium caused reduction of that bacteria number by ~30%,while Ruminococcus gauvreauii growth was slightly stimulated. Neither noni juice nor Citrosept influenced Bifidobacterium catenulatum growth. Concluding, dietary supplementation with some pharmaceuticals may exert a negative effect on human health instead of supporting it. The bioactive compound present in consumed pharmaceuticals can modulate the intestinal microbiota.
|Journal series||Potravinárstvo, ISSN 1338-0230, (B 5 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||antibacterial activity, grapefruit seed, intestinal microbiota, noni|
|Not used for evaluation||yes|
|Publication indicators||: 2014 = 0.037|
|Finansowanie||This project has been supported by a grant (decision number DEC-2011/01/B/NZ9/00226) from the National Science Care (NCN) and by a Scholarship of Rector of University of Agriculture in Krakow.|
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