Effective tool for assessment of the quality of barrier creams - relationships between rheological, textural and sensory properties
Agnieszka Kulawik-Pióro , Anna Ptaszek , Joanna Kruk
AbstractThe efficiency of barier creams (BC) in the prevention of occupational skin diseases is closely related to their mechanical, rheological but also sensory properties. The measurement procedure we elaborated, which simulates the spreadability conditions on the skin and evaluation whether the structure reconstruction occurs (hysteresis loop test, shear rate dependence of normal force), allows the assessment of the effectivness of the BC in terms of mechanical resistance and its adhesion to the skin surface. In this thesis an effort was made to define the impact of the human factor – the product application on skin – on the efficiency of medical devices for cutaneous use. Creams‘ performance such as the spreadability or the feeling on the skin during and after application, which mostly determine users willingness to use them systematically and rigorously, have been linked to parameters obtained during the structure analysis and to rheological properties. Moreover an attempt has been made to correlate the values of basic textural properties with rheological parameters determined by viscoelasticity and classic flow analysis. Instrumental analysis of selected BC products demonstrated a good correlation with organoleptic tests carried out on probands. The applicability of our tool for quality evaluation of BC has been confirmed.
|Journal series||Regulatory Toxicology and Pharmacology, ISSN 0273-2300, e-ISSN 1096-0295, (N/A 70 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||Skin barrier, Barrier creams, Texture profile, Sensory analysis, Quality of barrier creams, In vitro method|
|Publication indicators||= 0; : 2017 = 1.005; : 2018 = 2.996 (2) - 2018=2.821 (5)|
|Udział procentowy||A. Ptaszek: 50%, J. Kruk: 50%|
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