Functional properties of composites containing silver nanoparticles embedded in hyaluronan and hyaluronan-lecithin matrix

Gohar Khachatryan , Karen Khachatryan , Magdalena Krystyjan , Marcel Krzan , Lusine Khachatryan

Abstract

The rapid progress of nanotechnology triggers the development of nanomedicine. As the antimicrobial properties of nanosilver are well known, there is a huge interest in the synthesis of silver nanoparticles using environmentally-friendly methods. In this study we described the functional (rheological, mechanical, surface, structural) properties of gels and foils containing silver nanoparticles embedded in hyaluronan and hyaluronan-lecithin matrix prepared using the methods of green chemistry. The study showed that the addition of silver strengthened the structure of Hyal foil, but reduced the stretch of the sample and that lecithin weakened the mechanical properties of the composites. Also, the presence of nanosilver made the studied foils partially hydrophilic, while these with lecithin were more hydrophobic. The results of the study are significant for the adaptation of the investigated materials to their potential applications.
Author Gohar Khachatryan (FoFT / DoFAaQA)
Gohar Khachatryan,,
- Department of Food Analysis and Quality Assessment
, Karen Khachatryan (FoFT / DoCh)
Karen Khachatryan,,
- Department of Chemistry
, Magdalena Krystyjan (FoFT / DoCT)
Magdalena Krystyjan,,
- Department of Carbohydrate Technology
, Marcel Krzan - Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences (IKiFP PAN)
Marcel Krzan,,
-
, Lusine Khachatryan - The University Hospital in Cracow
Lusine Khachatryan,,
-
Journal seriesInternational Journal of Biological Macromolecules, ISSN 0141-8130, e-ISSN 1879-0003, (N/A 100 pkt)
Issue year2020
No149
Pages417-423
Publication size in sheets0.5
Keywords in EnglishHyaluronic acid, Silver nanoparticles, Lecithin
ASJC Classification2700 General Medicine; 1303 Biochemistry; 1312 Molecular Biology; 1315 Structural Biology
DOIDOI:10.1016/j.ijbiomac.2020.01.260
URL https://www.sciencedirect.com/science/article/pii/S0141813019387239
Languageen angielski
Score (nominal)100
Score sourcejournalList
Publication indicators WoS Citations = 0; Scopus SNIP (Source Normalised Impact per Paper): 2018 = 1.457; WoS Impact Factor: 2018 = 4.784 (2) - 2018=4.731 (5)
Citation count*
Additional fields
FinansowaniePart of this work was supported by National Science Centre of Poland (grant no. 2016/21/B/ST8/02107).
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