Effect of lettuce biofortified with iodine by soil fertilization on iodine concentration in various tissues and selected biochemical parameters in serum of Wistar rats
Aneta Kopeć , Ewa Piątkowska , Renata Bieżanowska-Kopeć , Mirosław Pysz , Aneta Koronowicz , Joanna Kapusta-Duch , Sylwester Smoleń , Roksana Rakoczy , Łukasz Skoczylas , Teresa Leszczyńska , Iwona Ledwożyw-Smoleń
AbstractIn this study, for the first time, we evaluated the effect of lettuce biofortified with iodine on iodine content in various tissues and selected biochemical parameters in the serum of Wistar rats. Significantly higher concentrations of iodine were measured in urine, faeces, hearts, and kidneys of rats fed the control diet (C diet) and the diet containing biofortified lettuce (BFL) compared to rats fed a diet containing non fortified-control lettuce or a diet with a lower level of iodine (equal to the content in control lettuce). Significantly higher concentrations of iodine were measured in the liver and femoral muscle of rats fed the BFL diet compared to the other experimental groups. Thyroid hormones, thyroid stimulating hormone, aspartate aminotransferase, alanine aminotransferase and selected genes' mRNA activities were not affected by the presence of biofortified lettuce in the diet compared to the control group. Biofortified lettuce may be considered as a potential source of iodine in the prevention of deficiency of this trace element.
|Journal series||Journal of Functional Foods, ISSN 1756-4646, (A 45 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||Iodine, Biofortification, Lettuce, Rats|
|ASJC Classification||; ;|
|Internal identifier||WBiO/8/45; WTŻ/P/9/2015; WTŻ/3/25; WTŻ/9/36|
|Publication indicators||= 11; : 2015 = 1.571; : 2015 = 3.973 (2) - 2015=4.269 (5)|
|Citation count*||6 (2016-09-03)|
|Finansowanie||This work was financed by the 2012–2015 Polish National Science Center – grant no. DEC-2011/03/D/NZ9/05560 “I and Se biofortification of selected vegetables, including the influence of these microelements on yield quality as well as evaluation of iodine absorption and selected biochemical parameters in rats fed with vegetables biofortified with iodine”.|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.