A Novel System for Patient Ventilation and Dosing of Hyperpolarized 3He for Magnetic Resonance Imaging of Human Lungs
Robert Kordulasiński , Marta Królewska , Bartosz Głowacz , Lutosława Mikowska , Zbigniew Olejniczak , Tadeusz Pałasz , Mateusz Suchanek , Winicjusz Filipow , Tomasz Dohnalik
AbstractA versatile ventilator for controlling a patient’s breath cycle and dosing 3He gas has been designed and constructed. It is compatible with a medical magnetic resonance imaging scanner and can be incorporated into routine human lungs imaging procedure that employs hyperpolarized noble gas as a contrast agent. The system adapts to the patient’s lung volume and their breath cycle rhythm, providing maximum achievable comfort during the medical examination. Good quality magnetic resonance lung images of healthy volunteers were obtained. The system has the capability of recycling the exhaled gas to recover the expensive 3He isotope, and can be also adapted to human lung imaging with hyperpolarized 129Xe.
|Journal series||Applied Sciences-Basel, [Applied Sciences (Switzerland)], ISSN 2076-3417, (N/A 70 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||3He; 129Xe; HP gas; ventilator; MRI; lung|
|ASJC Classification||; ; ; ; ;|
|License||Journal (articles only); author's original; ; after publication|
|Publication indicators||: 2018 = 0.985; : 2018 = 2.217 (2) - 2018=2.287 (5)|
|Licencja||This research was funded by the Polish National Center for Research and Development within the PBS program, edition 3, number PBS3/A9/35/2015.|
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