Premature centromere division (PCD) identified in a hucul mare with reproductive difficulties

Wojciech Witarski , Barbara Kij , Agnieszka Nowak , Monika Bugno-Poniewierska

Abstract

A hucul mare with reproductive abnormalities was examined during karyotype analysis. The karyotype was analysed based on evaluation of 860 metaphase plates in chromosome preparations. The use of fluorescence in situ hybridization (FISH) with an X chromosome painting probe showed premature X chromosome separation in 9.5% cases of examined chromosome spreads. In this report, we present the first identify premature centromere division (PCD) as a possible cause of abnormal X chromosome morphology in horses and as a probable cause of reproductive difficulties.
Author Wojciech Witarski
Wojciech Witarski,,
-
, Barbara Kij (FoAS / IoVS)
Barbara Kij,,
- Institute of Veterinary Sciences
, Agnieszka Nowak (FoAS / IoVS)
Agnieszka Nowak,,
- Institute of Veterinary Sciences
, Monika Bugno-Poniewierska (FoAS / IoVS)
Monika Bugno-Poniewierska,,
- Institute of Veterinary Sciences
Journal seriesReproduction in Domestic Animals, ISSN 0936-6768, e-ISSN 1439-0531, (N/A 100 pkt)
Issue year2020
Vol55
No2
Pages248-251
Publication size in sheets0.5
Keywords in EnglishFISH, horses, painting probe, premature centromere division, X chromosome
ASJC Classification1103 Animal Science and Zoology; 1305 Biotechnology; 1310 Endocrinology
DOIDOI:10.1111/rda.13605
URL https://onlinelibrary.wiley.com/doi/epdf/10.1111/rda.13605
Languageen angielski
Score (nominal)100
Score sourcejournalList
Publication indicators WoS Citations = 0; Scopus SNIP (Source Normalised Impact per Paper): 2017 = 0.934; WoS Impact Factor: 2018 = 1.638 (2) - 2018=1.677 (5)
Citation count*
Additional fields
FinansowanieThis research was funded by National Centre for Research and Development,. Grant Number: NCBiR:BIOSTRATEG2/297267/14/NCBR/2016
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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