Premature centromere division (PCD) identified in a hucul mare with reproductive difficulties
Wojciech Witarski , Barbara Kij , Agnieszka Nowak , Monika Bugno-Poniewierska
AbstractA hucul mare with reproductive abnormalities was examined during karyotype analysis. The karyotype was analysed based on evaluation of 860 metaphase plates in chromosome preparations. The use of fluorescence in situ hybridization (FISH) with an X chromosome painting probe showed premature X chromosome separation in 9.5% cases of examined chromosome spreads. In this report, we present the first identify premature centromere division (PCD) as a possible cause of abnormal X chromosome morphology in horses and as a probable cause of reproductive difficulties.
|Journal series||Reproduction in Domestic Animals, ISSN 0936-6768, e-ISSN 1439-0531, (N/A 100 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||FISH, horses, painting probe, premature centromere division, X chromosome|
|ASJC Classification||; ;|
|Publication indicators||: 2017 = 0.934; : 2018 = 1.638 (2) - 2018=1.677 (5)|
|Finansowanie||This research was funded by National Centre for Research and Development,. Grant Number: NCBiR:BIOSTRATEG2/297267/14/NCBR/2016|
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