Influence of Melatonin on Neutrophil to Lymphocyte Ratio in Mammalian Bloon Depending on Age of the Animal

Ludmila Uzenbaeva , Irina Vinogradova , Alexandra Kizhina , Olga Prokopenko , A. Malkiel , A. Goranskii , Stanisław Łapiński , Viktor Ilyukha


The influence of melatonin on the age dynamics of neutrophils and lymphocytes was investigated in the blood of laboratory rats kept under different light conditions and predatory mammals, including farmer silver foxes and raccoon dogs kept under natural light (NL). The decrease in the lymphocyte level, increase in the neutrophil content, and changes in the ratio of neutrophils to lymphocytes were detected in aged rats (24 months) kept under natural light (NL) and standard light (LD) and adult silver foxes (2–5 years) kept under natural light compared to juvenile animals. The reduced lymphocyte level and increased neutrophil level in rats under constant light (LL) were revealed at younger ages. The effect of melatonin was detected in aged rats and adult silver foxes and not observed in juvenile animals.
Author Ludmila Uzenbaeva
Ludmila Uzenbaeva,,
, Irina Vinogradova
Irina Vinogradova ,,
, Alexandra Kizhina
Alexandra Kizhina,,
, Olga Prokopenko
Olga Prokopenko,,
, A. Malkiel
A. Malkiel,,
, A. Goranskii
A. Goranskii,,
, Stanisław Łapiński (UAK)
Stanisław Łapiński,,
- University of Agriculture in Krakow
, Viktor Ilyukha
Viktor Ilyukha,,
Journal seriesAdvances in Gerontology, ISSN 2079-0570 , (0 pkt)
Issue year2013
Publication size in sheets0.5
Keywords in Englishleukocytes, leukogram, light condit ion, rat, silver fox, raccoon dog
Internal identifierWHiBZ/2013/32
Languageen angielski
Score (nominal)5
Score sourcejournalList
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