Effect of long term administration of resveratrol on lipid concentration in selected organs and liver’s histology in rats fed high fructose diet
Aneta Kopeć , Ewa Piątkowska , Teresa Leszczyńska , Aneta Koronowicz
AbstractThe aim of this study was to evaluate the effect of long term administration (4 months) of resveratrol (RSV) with high fructose (HF) diet (63%) on selected biochemical parameters and lipids content in different tissues of rats. Lipid profile in serum of rats was not affected by the addition of resveratrol to the experimental diets. The concentration of tiobarbituric acid reactive substances (TBARS; expressed as the melanodialdehyde – MDA equivalents) was significantly lower in the serum of rats fed HF diet with the addition of 0.04% and 0.06% of resveratrol. Crude lipids content in hearts was lower in rats fed with HF diet with the addition of 0.06% RSV. The concentration of lipids was also significantly lower in the liver of animals fed with HF diet with the addition of 0.04% or 0.06%. These results indicated that resveratrol significantly decreased fat accumulation and oxidative stress in rats fed with a high fructose diet.
|Journal series||Journal of Functional Foods, ISSN 1756-4646, (A 45 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||Resveratrol, High fructose diet, Lipids, Rats, Liver|
|Score|| = 35.0, 26-07-2017, ArticleFromJournal|
= 45.0, 26-07-2017, ArticleFromJournal
|Publication indicators||= 14|
|Citation count*||14 (2016-09-03)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.