Effect of long term administration of resveratrol on lipid concentration in selected organs and liver’s histology in rats fed high fructose diet

Aneta Kopeć , Ewa Piątkowska , Teresa Leszczyńska , Aneta Koronowicz

Abstract

The aim of this study was to evaluate the effect of long term administration (4 months) of resveratrol (RSV) with high fructose (HF) diet (63%) on selected biochemical parameters and lipids content in different tissues of rats. Lipid profile in serum of rats was not affected by the addition of resveratrol to the experimental diets. The concentration of tiobarbituric acid reactive substances (TBARS; expressed as the melanodialdehyde – MDA equivalents) was significantly lower in the serum of rats fed HF diet with the addition of 0.04% and 0.06% of resveratrol. Crude lipids content in hearts was lower in rats fed with HF diet with the addition of 0.06% RSV. The concentration of lipids was also significantly lower in the liver of animals fed with HF diet with the addition of 0.04% or 0.06%. These results indicated that resveratrol significantly decreased fat accumulation and oxidative stress in rats fed with a high fructose diet.
Author Aneta Kopeć (FoFT / DoHN)
Aneta Kopeć,,
- Department of Human Nutrition
, Ewa Piątkowska (FoFT / DoHN)
Ewa Piątkowska,,
- Department of Human Nutrition
, Teresa Leszczyńska (FoFT / DoHN)
Teresa Leszczyńska,,
- Department of Human Nutrition
, Aneta Koronowicz (FoFT / DoHN)
Aneta Koronowicz,,
- Department of Human Nutrition
Journal seriesJournal of Functional Foods, ISSN 1756-4646, (A 45 pkt)
Issue year2013
Vol5
No1
Pages299-305
Publication size in sheets0.5
Keywords in EnglishResveratrol, High fructose diet, Lipids, Rats, Liver
DOIDOI:10.1016/j.jff.2012.10.020
URL http://ac.els-cdn.com/S1756464612001661/1-s2.0-S1756464612001661-main.pdf?_tid=d3a45e92-5b77-11e5-9622-00000aacb362&acdnat=1442300771_82dee1cebe52074a1d49ec3a0a6b4378
Internal identifierWTŻ/2013/29
Languageen angielski
Score (nominal)45
ScoreMinisterial score = 35.0, 26-07-2017, ArticleFromJournal
Ministerial score (2013-2016) = 45.0, 26-07-2017, ArticleFromJournal
Publication indicators WoS Citations = 14
Citation count*14 (2016-09-03)
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