The Synthesis of 1H-Pyrazolo[3,4-b]quinoxaline Derivatives Oriented towards Modification of Carbocyclic Ring in the Parent Skeleton

Katarzyna Wojtasik , Andrzej Danel

Abstract

Palladium catalyzed aminoarylation reactions are widely used to create new C−N bonds. It has been proved that the method of synthesis of 1H ‐pyrazolo[3,4‐b ]quinoxaline derivatives (PQX), consisting of the reductive cyclization of the corresponding pyrazole derivative, is the most universal method of PQX synthesis among the known and is regiospecific. The obtained x‐chloro‐1‐methyl‐3‐phenyl‐1H ‐pyrazolo[3,4‐b ]quinoxaline isomers were starting materials for the synthesis of N,N ‐diethylamine derivatives. The position differentiation of these substituents strongly impact the emissive properties of the final compounds.
Author Katarzyna Wojtasik (FoFT / DoCh)
Katarzyna Wojtasik,,
- Department of Chemistry
, Andrzej Danel (FoFT / DoCh)
Andrzej Danel,,
- Department of Chemistry
Journal seriesChemistrySelect, ISSN 2365-6549, (N/A 40 pkt)
Issue year2020
Vol5
No19
Pages5521-5525
Publication size in sheets0.5
Keywords in English1H-pyrazolo[3,4-b]quinoxaline, amination, Pd2dba3, reductive cyclisation, regioselectivity
DOIDOI:10.1002/slct.202000418
URL http://doi.org/10.1002/slct.202000418
Languageen angielski
Score (nominal)40
Score sourcejournalList
Publication indicators WoS Citations = 0; WoS Impact Factor: 2018 = 1.716 (2) - 2018=1.716 (5)
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Dyscypliny zgłoszone przez:K. Wojtasik
LicencjaBrak szczegółowej informacji
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